Sickle Cell Anemia

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sickle cell Anemia

        Sickle Cell Anemia is the most common hematologic hereditary derange know

toman. It is a condition where the red blood cells (RBC) sometimes strike a

strange,sickle©like shape. Observations date back to Herrick in 1910, but the

molecularera for the debate of Sickle Cell Anemia did not begin until the identification

ofHemoglobin S (Hb S), by Linus Pauling in 1949. It is a world©health

problempredominantly affecting Negroes in the Untied States and Africa, and

sometimesLatins. 50% of those with Sickle Cell Anemia collapse before age 20, and most do

notlive to reach age 40.

         familiar Red Blood Cells are shaped similar to donuts, and devolve easily through and throughthe

blood stream to carry Oxygen to ALL part of the body. Sickle cells, because ofthere odd

shape, do not easily pass through the blood vessels and tend to clog them,because of this,

internal organs may not receive enough oxygen.

        I in 10 African©Americans carry the gene, and about 1 in 400

African©Americanchildren carry Sickle Cell Anemia.

        If a person is hybrid for the disease, they are verbalise to have the sickle cell character.

Their cells can be made to sickle in a test tube, and under extremeconditions of exercise,

and at lavishly altitudes.



This is rare and seldom serious,most people with the trait live full,

normal lives. The trait can never turn intothe anemia.

        About 50% of the children of to parents who some(prenominal) have the trait give also havethe

trait. About 25% will be born with the anemia, and about 25% will not beaffected by

ether one.

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T T A N

        Sickle Cell Anemia affects...

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